Robert Wilms

Wilms Tumor

[Wilms' tumor].

Today the prognosis in children with nephroblastoma is excellent. With the combination of surgery, chemotherapy and radiation more than 80% of children can be cured. Because of acute toxicity and late effects of treatment (scoliosis, cardiotoxicity, fertility problems and second malignancies) a major issue in the management of children with this kind of malignancy is the reduction of chemothera...

Robert Insall

Robert Insall was born in London in 1965, into a family of architects, musicians and historians. To their great surprise, he was obviously scientifically inclined from an early age. He did a B.A. at Cambridge University, then stuck around in Cambridge for a Ph.D., where he got interested in Dictyostelium, followed by a postdoc in Johns Hopkins, where he got interested in chemotaxis and cell mov...

Robert Koch

Robert Dottin

We are investigating the signal transduction mechanisms by which extracellular hydrophilic hormones activate genes. We use Dictyostelium discoideum as a model eukaryote because it is relatively easy to perform reverse genetics on this organism and it is also capable of development. We had earlier shown that extracellular cAMP behaves as a hydrophilic